Rams vs. 49ers predictions, odds, injury news for Sunday’s game

September 17, 2023;  Inglewood, California, United States;  Los Angeles Rams running back Kyren Williams (23) runs the ball against the San Francisco 49ers during the second half at SOFI Stadium.  Mandatory Credit: Gary A. Vasquez-USA TODAY Sports

THE NFL Week 18 Action features numerous division matchups across the league, including the NFC West. The division champion San Francisco 49ers (12-4) will welcome the Los Angeles Rams (9-7) Sunday at Levi's Stadium in Santa Clara, California.

The Rams enter Week 18 as one of the hottest teams in the NFL. Los Angeles is 6-1 in its last seven games since a Week 10 bye; THE the only loss came in week 14 against the leader of the AFC Baltimore Ravens. The Rams offense is averaging over 400 yards and nearly 30 points per game during this stretch. Los Angeles has Pro Bowl players at quarterback (Matthew Stafford), to come back (Kyren Williams), and wide receiver (Puka Nacua). These starters and many others will not participate in this game because the Rams have already clinched a playoff spot.

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